I run into this problem when I tried to install Tweetdeck app on my new macbook pro with Mac OS X 10.6.4 Snow Leopard. Adobe Air installation is required before you can install Tweetdeck on any computer. I can install both Adobe Air and Tweetdeck, but when I open Tweetdeck, it shows up an error that Adobe Air is damaged blah blah blah.
I asked for support from Adobe’s forum and after 22 days of waiting, they sent me an applescript which solved the problem.
adobe air for mac, install tweetdeck